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  • Writer's pictureNick Tetlow

Spotlight: Mitochondrial function is impaired in the skeletal muscle of pre-frail elderly.

Updated: Jan 25, 2023

This month the spotlight is on 'Mitochondrial function is impaired in the skeletal muscle of pre-frail elderly'.



Andreux et al., 2018 highlights mitochondrial impairment in the elderly is a key marker of pre-frailty and alludes to the deterioration of normal skeletal muscle function. A key finding from this study was compared to active individuals, the pre-frail population saw significant reduced phosphocreatine recovery.


This research aligns with our mission to discover whether frailty pre-surgery can predict outcomes post-surgery.



Andreux, P. A. et al. Mitochondrial function is impaired in the skeletal muscle of pre-frail elderly. Sci. Rep. (2018). doi:10.1038/s41598-018-26944-x




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