Publications

Wong HY, Starsmore L, Tetlow N, Dewar A, Chapman O, Lipman J, Pidding J, Montanheiro K, Bellin U, Whittle J. Implementation of a surgical prehabilitation pathway at a tertiary surgical centre during a global pandemic. BJA Open. 2022 Oct 1;4. doi:https://doi.org/10.1016/j.bjao.2022.100069

Tetlow N, Dewar A, Sleeman A, Yu N, Vinnakota K, Arina P, Aliukaite S, Clark S, Arulkumaran N, Tan M, Sridhar A. Preoperative Metabolic Inflexibility is Associated with the Development of Postoperative Morbidity after Radical Cystectomy. link to abstract

Lalabekyan BB, Tetlow N, Moonesinghe R, Martin D, Burdett E, Otto J, Wyndham D, Bettini E, Kalavrezos N, Stephens RC. Cardiopulmonary exercise testing and cardiopulmonary morbidity in patients undergoing major head and neck surgery. British Journal of Oral and Maxillofacial Surgery. 2021 Apr 1;59(3):297-302. doi:https://doi.org/10.1016/j.bjoms.2020.08.032

Nelson AW, Arianayagam R, Umari P, Campbell E, Tetlow N, Duncan J, Baker H, Parker J, Lucetta C, Perkins R, Tan M. Components of a safe cystectomy service during coronavirus disease 2019 in a high-volume centre. Journal of Clinical Urology. 2022 Mar;15(2):133-40. https://doi.org/10.1177/2051415820970370

Dewar A, Kass L, Stephens RC, Tetlow N, Desai T. Heart Rate Recovery Assessed by Cardiopulmonary Exercise Testing in Patients with Cardiovascular Disease: Relationship with Prognosis. International Journal of Environmental Research and Public Health. 2023 Mar 7;20(6):4678. doi:https://doi.org/10.3390/ijerph20064678

Publications

Whittle, J., Coleman, D., Molinger, J., Inman, B., & MacLeod, D. B. (2022). Metabolic flexibility in patients undergoing Radical Cystectomy. ANESTHESIA AND ANALGESIA, 134, 971-972. LIPPINCOTT WILLIAMS & WILKINS.

Bishawi, M., Kaplan, M., Chidyagwai, S., Cappiello, J., Cherry, A., MacLeod, D., . . . Randles, A. (2022). Patient- and Ventilator-Specific Modeling to Drive the Use and Development of 3D Printed Devices for Rapid Ventilator Splitting During the COVID-19 Pandemic. In D. Groen, C. DeMulatier, M. Paszynski, V. V. Krzhizhanovskaya, J. J. Dongarra, P. M. A. Sloot (Eds.), null(pp. 137-149). SPRINGER INTERNATIONAL PUBLISHING AG. doi:10.1007/978-3-031-08757-8_13
Whittle, J., & San-Millan, I. (2021). Objective assessment of metabolism and guidance of ICU rehabilitation with cardiopulmonary exercise testing. CURRENT OPINION IN CRITICAL CARE, 27 (4), 390-398. doi:10.1097/MCC.0000000000000843
Niederer, L. E., Miller, H., Haines, K. L., Molinger, J., Whittle, J., MacLeod, D. B., . . . Wischmeyer, P. E. (2021). Prolonged Progressive Hypermetabolism during COVID-19 Hospitalization Undetected by Common Predictive Energy Equations. Clinical Nutrition ESPEN. doi:10.1016/j.clnesp.2021.07.021
Gunnarsdottir, G. M., Helgadottir, S., Einarsson, S. G., Hreinsson, K., Whittle, J., Karason, S., & Sigurdsson, M. I. (2021). Validation of the Hospital Frailty Risk Score in older surgical patients: A population-based retrospective cohort study. ACTA ANAESTHESIOLOGICA SCANDINAVICA, 65 (8), 1033-1042. doi:10.1111/aas.13837
Grimberg, D. C., Shah, A., Molinger, J., Whittle, J., Gupta, R. T., Wischmeyer, P. E., . . . Inman, B. A. (2020). Assessments of frailty in bladder cancer. UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, 38 (9), 698-705. doi:10.1016/j.urolonc.2020.04.036
Ohnuma, T., Raghunathan, K., Moore, S., Setoguchi, S., Ellis, A. R., Fuller, M., . . . Krishnamoorthy, V. (2020). Dose-Dependent Association of Gabapentinoids with Pulmonary Complications After Total Hip and Knee Arthroplasties. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 102 (3), 221-229. doi:10.2106/JBJS.19.00889
Ohnuma, T., Raghunathan, K., Ellis, A. R., Whittle, J., Pyati, S., Bryan, W. E., . . . Krishnamoorthy, V. (2020). Effects of Acetaminophen, NSAIDs, Gabapentinoids, and Their Combinations on Postoperative Pulmonary Complications After Total Hip or Knee Arthroplasty. PAIN MEDICINE, 21 (10), 2385-2393. doi:10.1093/pm/pnaa017
Molinger, J., Pastva, A. M., Whittle, J., & Wischmeyer, P. E. (2020). Novel approaches to metabolic assessment and structured exercise to promote recovery in ICU survivors. Current Opinion in Critical Care, Publish Ahead of Print. doi:10.1097/mcc.0000000000000748
Martin, G. S., Kaufman, D. A., Marik, P. E., Shapiro, N. I., Levett, D. Z. H., Whittle, J., . . . Miller, T. E. (2020). Perioperative Quality Initiative (POQI) consensus statement on fundamental concepts in perioperative fluid management: fluid responsiveness and venous capacitance. Perioperative Medicine, 9 (1), 12. doi:10.1186/s13741-020-00142-8
Whittle, J., Molinger, J., MacLeod, D., Haines, K., & Wischmeyer, P. E. (2020). Persistent hypermetabolism and longitudinal energy expenditure in critically ill patients with COVID-19. CRITICAL CARE, 24 (1), ARTN 581. doi:10.1186/s13054-020-03286-7
Whitby, J., Bampoe, S., Fullerton, J. N., Smaje, A., Hornby, J., Hajdu, B., . . . Davis, D. (2020). Prospective Investigation of Markers of Elevated Delirium Risk (PRIMED Risk) study protocol: a prospective, observational cohort study investigating blood and cerebrospinal fluid biomarkers for delirium and cognitive dysfunction in older patients [version 1; peer review: awaiting peer review]. Wellcome Open Research, 5, 5. doi:10.12688/wellcomeopenres.15658.1
VanDusen, K. W., Eleswarpu, S., Moretti, E. W., Devinney, M. J., Crabtree, D. M., Laskowitz, D. T., . . . Zani, S. (2020). The MARBLE Study Protocol: Modulating ApoE Signaling to Reduce Brain Inflammation, DeLirium, and PostopErative Cognitive Dysfunction. JOURNAL OF ALZHEIMERS DISEASE, 75 (4), 1319-1328. doi:10.3233/JAD-191185
Lenk, T., Whittle, J., Miller, T. E., Williams, D. G. A., & Bronshteyn, Y. S. (2019). Focused cardiac ultrasound in preoperative assessment: the perioperative provider's new stethoscope?. PERIOPERATIVE MEDICINE, 8 (1), ARTN 16. doi:10.1186/s13741-019-0129-8

Wong, H. -. Y., Starsmore, L., Tetlow, N., Dewar, A., Chapman, O., Lipman, J., . . . Whittle, J. (2022). Implementation of a surgical prehabilitation pathway at a tertiary surgical centre during a global pandemic. BJA Open, 4, 100069. doi:10.1016/j.bjao.2022.100069

Ackland, G. L., Abbott, T. E. F., Cain, D., Edwards, M. R., Sultan, P., Karmali, S. N., . . . Pearse, R. M. (2019). Preoperative systemic inflammation and perioperative myocardial injury: prospective observational multicentre cohort study of patients undergoing non-cardiac surgery. BRITISH JOURNAL OF ANAESTHESIA, 122 (2), 180-187. doi:10.1016/j.bja.2018.09.002
Ackland, G. L., Abbott, T. E. F., Pearse, R. M., Karmali, S. N., Whittle, J., & Minto, G. (2018). Arterial pulse pressure and postoperative morbidity in high-risk surgical patients. BRITISH JOURNAL OF ANAESTHESIA, 120 (1), 94-100. doi:10.1016/j.bja.2017.11.009
Ackland, G. L., Minto, G., Clark, M., Whittle, J., Stephens, R. C. M., Owen, T., . . . del Arroyo, A. G. (2018). Autonomic regulation of systemic inflammation in humans: A multi-center, blinded observational cohort study. BRAIN BEHAVIOR AND IMMUNITY, 67, 47-53. doi:10.1016/j.bbi.2017.08.010
Whittle, J., Wischmeyer, P. E., Grocott, M. P. W., & Miller, T. E. (2018). Surgical Prehabilitation: Nutrition and Exercise. Anesthesiology Clinics, 36 (4), 567-580. doi:10.1016/j.anclin.2018.07.013
Machhada, A., Trapp, S., Marina, N., Stephens, R. C. M., Whittle, J., Lythgoe, M. F., . . . Gourine, A. V. (2017). Vagal determinants of exercise capacity. Nature communications, 8, 15097. doi:10.1038/ncomms15097

Dunkman, W. J., Manning, M. W., Whittle, J., Hunting, J., Rampersaud, E. N., Inman, B. A., . . . Miller, T. E. (2019). Impact of an enhanced recovery pathway on length of stay and complications in elective radical cystectomy: a before and after cohort study. PERIOPERATIVE MEDICINE, 8 (1), ARTN 9. doi:10.1186/s13741-019-0120-4

Nelson, A., Otto, J., Whittle, J., Stephens, R. C., Martin, D. S., Prowle, J. R., & Ackland, G. L. (2016). Subclinical cardiopulmonary dysfunction in stage 3 chronic kidney disease. Open heart, 3 (1), e000370. doi:10.1136/openhrt-2015-000370
Barsukevich, V., Basalay, M., Sanchez, J., Mrochek, A., Whittle, J., Ackland, G. L., . . . Gourine, A. (2015). Distinct cardioprotective mechanisms of immediate, early and delayed ischaemic postconditioning. Basic Res Cardiol, 110 (1), 452. doi:10.1007/s00395-014-0452-7

Ackland, G. L., Whittle, J., Toner, A., Machhada, A., Del Arroyo, A. G., Sciuso, A., . . . Gourine, A. V. (2016). Molecular Mechanisms Linking Autonomic Dysfunction and Impaired Cardiac Contractility in Critical Illness. CRITICAL CARE MEDICINE, 44 (8), E614-E624. doi:10.1097/CCM.0000000000001606

Ackland, G. L., Iqbal, S., Paredes, L. G., Toner, A., Lyness, C., Jenkins, N., . . . POM-O (PostOperative Morbidity-Oxygen delivery) study group. (2015). Individualised oxygen delivery targeted haemodynamic therapy in high-risk surgical patients: a multicentre, randomised, double-blind, controlled, mechanistic trial. Lancet Respir Med, 3 (1), 33-41. doi:10.1016/S2213-2600(14)70205-X
Edwards, M. R., Sultan, P., del Arroyo, A. G., Whittle, J., Karmali, S. N., Moonesinghe, S. R., . . . Ackland, G. L. (2015). Metabolic dysfunction in lymphocytes promotes postoperative morbidity. CLINICAL SCIENCE, 129 (5), 423-437. doi:10.1042/CS20150024
Whittle, J., & Kelleher, A. A. (2015). Preoperative assessment for cardiac surgery. Anaesthesia and Intensive Care Medicine, 16 (10), 484-490. doi:10.1016/j.mpaic.2015.07.009
Whittle, J., Nelson, A., Otto, J. M., Stephens, R. C. M., Martin, D. S., Sneyd, J. R., . . . Ackland, G. L. (2015). Sympathetic autonomic dysfunction and impaired cardiovascular performance in higher risk surgical patients: implications for perioperative sympatholysis. Open Heart, 2 (1), e000268-?. doi:10.1136/openhrt-2015-000268

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